Default Mode Network (default attention)

Summary and Support

• An analysis of research studies on the default mode network indicates the following:
  • The strength of the functional connectivity of the default mode network is lowest in children and the elderly and is highest in adults.
  • The functional connectivity of the default mode network is positively correlated with cognitive function.
  • Compared to males, females demonstrate stronger intra-network connectivity.
  • Findings following a voxel-wise meta-analysis seem to show that adults have a stronger network than do the elderly, and a more mature network than do children.
  • The findings of the analysis may assist the understanding of normal variance.
  • The use of a normal comparative base to identify changes in the default mode network may potentially help detect risk phenotypes and assist treatment responses.

Contributors

Ayesh Perera